One thing I have noticed if you take your pano photo and try to edit it in lightroom all it does is bring out more defects. I also have problems using PanoramaStudio 3 Pro as it seems to have trouble stitching all the photos.
Unedited
generated_10000023_SPHERE_HQ.
Edited in lightroom
generated_10000023_SPHERE_HQ.
Unedited
generated_10000023_SPHERE_HQ.
Edited in lightroom
generated_10000023_SPHERE_HQ.